Yep, that was a smiling intestine in a Super Bowl commercial

It’s pretty unnerving right from the jump.

Earlier in Super Bowl 50, America bore witness to a commercial featuring a baby who really liked Doritos — so much so that he made an early exit from the womb. It was the weirdest commercial of the night.

Now, we’ve got an anthropomorphized lower intestine battling a debilitating case of diarrhea so he can watch the big game. Yes, it’s been a very strange night.

The commercial for Xifaxan, a prescription medication by Valean Pharmaceuticals used to treat irritable bowel syndrome or traveler’s diarrhea, took the Internet by storm.

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Check out the vaguely unsettling ad below.


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