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Profession Education: Formulation and Stabilization of Biotherapeutics

MIT

Wednesday • June 12

Clock Icon 9:00 AM
Money Icon $3900
Location Icon MIT
77 Massachusetts Ave
Cambridge, MA 02139
External Link Icon

Event Details

Biotherapeutics are complex sets of molecules with numerous routes of both chemical and physical instability, which can manifest from development to manufacturing. Addressing these instabilities is a great challenge, because of the complexity of the biotherapeutics themselves, the mechanisms of instability, and the approaches to solve them. 

This course addresses those challenges, focusing on globular proteins and antibodies, but also addressing peptides, vaccines, antibody-drug conjugates, and other modalities in a variety of situations from low to high concentration liquid formulations to lyophilized formulations to various manufacturing unit operations. The approach is to identify potential routes of instability as early on as discovery, and use rational and mechanistic approaches to solve them.

This 4-day course meets June 10-13, 2019 from 9:00am-5:00pm, except for Thursday when it ends at 12:00pm. Course fee is $3,900. Register now to secure your spot.

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